Category Archives: Psychosis

Antipsychotic Discontinuation in Recovered First-Episode Psychosis Results in Relapse

A study published in the Journal of Clinical Psychiatry evaluated the risk of symptom recurrence over 3 years after antipsychotic discontinuation in a sample of functionally recovered first-episode nonaffective psychosis (FEP) patients with schizophrenia spectrum disorder. When to discontinue antipsychotic … Continue reading

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The Myth of Schizophrenia as a Progressive Brain Disease

Schizophrenia has historically been considered to be a deteriorating disease, a view reinforced by recent MRI findings of progressive brain tissue loss over the early years of illness. Zipursky and colleagues challenge this concept. Schizophrenia Bulletin [More…]

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Sixth Annual Chair Summit Begins This Week

This week a Master Class for Neuroscience Development called the Chair Summit takes place in Tampa, FL (Sept 26-28, 2013). In the early days of medical training in Kos, students, trainees and medical colleagues would gather to discuss their cases … Continue reading

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Essential Components of First-Episode Psychosis Services

A study published in May 1st, 2013 Psychiatric Services identified essential evidence-based components of first-episode psychosis services. The research took place in two stages. First a systematic literature review, then, a consensus-building technique, the Delphi, was used with an international … Continue reading

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The Nature of Relapse in Schizophrenia

Discontinuation of treatment in schizophrenia results in very high relapse rates, even after a single psychotic episode. A new review in BMC Psychiatry asserts that multiple relapses characterze the course of illness in most patients with schizophrenia, yet the nature … Continue reading

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Non-adherence to Antipsychotics and Cardiometabolic Medication Result in Health Care Utilization and Costs

A new study in Psychiatric Services examined the association between adherence to antipsychotic and cardiometabolic medication and the use of health care services and expenditures. A total of 87,015 unique patients with schizophrenia who received at least one antipsychotic medication … Continue reading

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Early Detection and Intervention in Psychosis Improves 10-Year Outcome

Early detection in first-episode psychosis confers advantages for negative, cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects have been unknown. A new article  published in the American Journal of Psychiatry investigated the differences in symptoms … Continue reading

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Chair Summit Meeting Highlights – available now in HORM

Article series from the 3rd Annual Chair Summit, The Master Class for Neuroscience Professional Development (Chair Summit) available now in Health Outcomes Research in Medicine journal (HORM) The continuing professional development of clinicians protects one of our nation’s most precious … Continue reading

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Persistent negative symptoms in first-episode schizophrenia

A study published in Schizophrenia Research describes that negative symptoms, which are a core feature of schizophrenia, are generally understudied. Researchers evaluated the prevalence and stability of primary negative symptoms, and factors associated with persistent primary negative symptoms in a … Continue reading

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New Guide to the Management of Psychotic Disorders in Older Adults

The American Geriatrics Society‘s newest clinical tool, the AGS Guide to the Management of Psychotic Disorders and Neuropsychiatric Symptoms of Dementia in Older Adults, is now available on the AGS website.[Read more]

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