Category Archives: Biomarker

New Classification Scheme for Alzheimer’s Biomarkers

The American Academy of Neurology is proposing a new classification scheme to describe Alzheimer’s biomarkers. Biomarkers have become an essential component of Alzheimer disease (AD) research and also in cognitive aging research. A number of current issues suggest that a new … Continue reading

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Diagnostic Method for Alzheimer’s from Sweden Becomes International Standard

Researchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer’s disease decades before symptoms appear. The method has now formally been classified as the international reference method, which means that it will be used as … Continue reading

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Preventive Neuroradiology in Brain Aging and Cognitive Decline

A new review published online in American Journal of Neuroradiology highlights the concept that cognitive decline can be identified early and prevented by applying quantitative brain imaging techniques. [More]

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Sense of Smell May Predict Risk for Cognitive Decline

Two studies presented at the 2014 Alzheimer’s Association International Conference (AICC) in Copenhagen this month demonstrated that a decrease in the ability to identify odors was significantly associated with loss of brain cell function and progression to Alzheimer’s disease. There is growing evidence … Continue reading

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Sixth Annual Chair Summit Begins This Week

This week a Master Class for Neuroscience Development called the Chair Summit takes place in Tampa, FL (Sept 26-28, 2013). In the early days of medical training in Kos, students, trainees and medical colleagues would gather to discuss their cases … Continue reading

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Targeting Inflammation in Treatment Resistant Depression

Research published in this month’s Archives of General Psychiatry evaluated the use of a monoclonal antibody (mAb) against tumor necrosis factor (TNF) alpha for treatment resistant depression. Researchers at Emory University studied whether blocking inflammation would be a useful treatment … Continue reading

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The Effects of General Medical Health on Alzheimer’s Progression Revisited

For several years, studies have suggested that there is a link between health status or lifestyle and rate of progression in Alzheimer’s disease. Research on published in International Psychogeriatrics studied 335 individuals diagnosed with dementia for 11 years in a … Continue reading

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The MAOA Gene Predicts Happiness in Women

Research published in Progress in Neuro-Psychopharmacology and Biological Psychiatry demonstrates the association between happiness and monoamine oxidase A (MAOA) genotype. In women, low expression of MAOA was related significantly to greater happiness. In contrast, no such association was found in … Continue reading

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Personalized Medicine in Psychiatry

How close are we to implementing the idea of personalized medicine in psychiatry? Next year the International Congress on Neuropsychopharmacology (CINP) is holding a thematic meeting in April 2013 entitled “Pharmacogenomics and Personalized Medicine in Psychiatry.” An ‘All Star’ plenary … Continue reading

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Alzheimer’s Biomarker and Major Depression

Research published in the American Journal of Psychiatry demonstrates that elderly patients who are cognitively intact and diagnosed with major depression may have low levels of amyloid beta 42 (Aß-42) in cerebral spinal fluid (CSF). Aß-42 has been implicated in … Continue reading

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