Monthly Archives: July 2012

Transcranial Magnetic Stimulation (TMS) For Major Depression: A Naturalistic Study

In one of the first studies to look at transcranial magnetic stimulation (TMS) in real-world clinical practice settings, researchers confirmed that TMS is an effective treatment for patients with depression who are unable to find symptom relief through antidepressant medications. … Continue reading

Posted in Depression, Transcranial magnetic stimulation | Comments Off on Transcranial Magnetic Stimulation (TMS) For Major Depression: A Naturalistic Study

Beyond Dopamine: Glutamate as a Target in Schizophrenia

An interesting review in ISRN Pharmacology, a peer-reviewed, open access journal, describes that for the last 60 years, antipsychotic pharmacology targeting antagonism of dopamine (DA) D2 receptors have been the primary treatment choice for schizophrenia. The clinical improvement seen by … Continue reading

Posted in Antipsychotic medication, Cognition, Negative symptoms, Schizophrenia | Comments Off on Beyond Dopamine: Glutamate as a Target in Schizophrenia

Personalized Medicine in Psychiatry

How close are we to implementing the idea of personalized medicine in psychiatry? Next year the International Congress on Neuropsychopharmacology (CINP) is holding a thematic meeting in April 2013 entitled “Pharmacogenomics and Personalized Medicine in Psychiatry.” An ‘All Star’ plenary … Continue reading

Posted in Biomarker, Depression, Genetics, Schizophrenia | Comments Off on Personalized Medicine in Psychiatry

Negative symptoms and depression predict poorer psychological well-being in individuals with schizophrenia

A study published in Comprehensive Psychiatry evaluated the impact of negative symptoms and depression on psychological well-being in individuals with schizophrenia. A number of previous studies have demonstrated that negative symptoms are linked to lower rates of recovery in individuals … Continue reading

Posted in Depression, Negative symptoms, Schizophrenia | Comments Off on Negative symptoms and depression predict poorer psychological well-being in individuals with schizophrenia

The Influence of Genetics on High ACPA Levels in Rheumatoid Arthritis

A recent study in the Journal Arthritis and Rheumatism assessed whether extreme production of a very specific biomarker in rheumatoid arthritis (RA) called anti-citrullinated protein antibodies (ACPAs) has any genetic associations. High levels of ACPA are frequently associated with a … Continue reading

Posted in Rheumatoid arthritis | Comments Off on The Influence of Genetics on High ACPA Levels in Rheumatoid Arthritis

Alice in Wonderland and Sleep Apnea

An interesting review in the Oxford University Press blog by Edward Shorter, MD, Professor in the History of Medicine and Professor of Psychiatry, University of Toronto and Susan Bélanger, Research Coordinator with the History of Medicine Program discusses “Alice in … Continue reading

Posted in History, Sleep, Sleep Apnea | Comments Off on Alice in Wonderland and Sleep Apnea

Brain Regions Involved in Transition From Acute to Chronic Pain

Neuroscience researchers have been searching for years using imaging studies to find changes in brain structure and function that correlate with persistent pain. A recent study in Nature Neuroscience studied patients (n=40) with subacute back pain (SBP) lasting 4–16 weeks, … Continue reading

Posted in Brain Scan, Imaging, Pain, Radiology | Comments Off on Brain Regions Involved in Transition From Acute to Chronic Pain